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1450–1750: Science & Technology

 
1460   Italy: Production of clear glass perfected
 
1469   First printed version of Pliny the Elder’s Natural History
 
c. 1480   Aztec sun stone calendar
 
c. 1480   First use of plus and minus signs
 
1480–1520   Italian inventor and artist Leonardo da Vinci conceives of the parachute, helicopter, and wheel-lock musket
 
1492   Christopher Columbus reaches North America
 
1498   Vasco de Gama reaches Calicut, India
 
c. 1500   Germany: Peter Henlein invents pocketwatch
 
1510   Polish astronomer Copernicus theorizes that Earth revolves around the sun
 
1564–1642   Galileo Galilei
 
1582   Gregorian calendar introduced under Pope Gregory XIII
 
1593   First modern abacus in China
 
1619   Germany: Johannes Kepler develops laws of planetary motion
 
1621   First modern army under Gustavus II of Sweden
 
1623–1662   French scientist Blaise Pascal
 
1628   England: William Harvey describes circulation of blood
 
1637   René Descartes proposes analytical geometry
 
1659   Fermat’s theory of probability
 
1662   Royal Society of London founded
 
c. 1665   England: Isaac Newton develops law of gravity
 
1665–1675   Royal observatories constructed in Paris and Greenwich
 
1673   Marquette and Joliet explore Upper Mississippi
 
1701   England: Jethro Tull invents seed drill
 
1709   England: Process of producing iron in blast furnace
 
1714   Germany: Fahrenheit uses mercury to create thermometer
 
1721   Boston: First smallpox inoculations
 
1730   Bering Strait mapped and named
 
1733   Englishman John Kay invents flying shuttle loom
 
1735   Sweden: Carl Linnaeus develops system of taxonomic classification
 
1740–1742   Processes of casting and galvanizing steel advanced
 
c. 1750   Beginning of the Industrial Revolution